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Leukemia

Leukemia - Scientific exchange

Learn more about innovative studies and new treatment options for leukemia. Your participation could be crucial!

Ongoing Studies

Recruitment completed

CLL 17

A prospective, randomized, unblinded, multicenter, phase III study comparing the efficacy and safety of ibrutinib monotherapy versus time-limited therapy with venetoclax plus obinutuzumab or ibrutinib plus venetoclax in patients with previously untreated chronic lymphocytic leukemia (CLL) - CLL17
Recruitment completed

HOVON 150

A multicenter, double-blind, randomized, placebo-controlled phase 3 study of ivosidenib or enasidenib in combination with induction therapy and consolidation therapy followed by maintenance therapy in patients with newly diagnosed acute myeloid leukemia or myelodysplastic syndrome with blast excess-2, with an IDH1 or IDH2 mutation, respectively, who are eligible for intensive chemotherapy.
Recruitment completed

HOVON 155

A randomized phase II multicenter study to assess the tolerability and efficacy of the addition of midostaurin to 10-day decitabine in unfit (i.e. HCT-CI ≥ 3) adult AML and high risk myelodysplasia (MDS) (IPSS-R > 4.5) patients. A study in the frame of the masterprotocol of parallel randomized phase II studies in UNFIT- AML/high-risk MDS patients.
Recruitment completed

HOVON 156

A phase 3, multicenter, open-label, randomized, study of Gilteritinib versus Midostaurin in combination with induction and consolidation therapy followed by one-year maintenance in patients with newly diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic syndromes with excess blasts-2 (MDS-EB2) with FLT3 mutations eligible for intensive chemotherapy.

Leukemia project group

The researchers working in the network maintain a regular scientific exchange in indication-specific project group meetings. At the project group meetings, study proposals are initiated, further developed and submitted to the Executive Board for evaluation.

The Leukemia Project Group is made up of medical oncologists and representatives from other disciplines.